Roitt’s Essential Immunology – 12th Edition

About the Author

Seamus J. Martin
Professor Martin received his PhD from The National University of Ireland in 1990 and trained as a post‐doctoral fellow at University College London (with Ivan Roitt) and The La Jolla Institute for Allergy and Immunology, California, USA (with Doug Green). Since 1999, he is the holder of the Smurfit Chair of
Medical Genetics at Trinity College Dublin and is also a Science Foundation Ireland Principal Investigator. His research is focused on various aspects of programmed cell death (apoptosis) in the immune system and in cancer and he has received several awards for his work in this area. He has previously edited two books on apoptosis and was elected as a Member of The Royal Irish Academy in 2006 and as a member of The European Molecular Biology
Organisation (EMBO) in 2009.

Dennis R. Burton
Professor Burton obtained his BA in Chemistry from the University of Oxford in 1974 and his PhD in Physical Biochemistry from the University of Lund in Sweden in 1978. After a period at the University of Sheffield, he moved to the Scripps Research Institute in La Jolla, California in 1989 where he is Professor of Immunology and Microbial Science. His research interests include antibodies, antibody responses to pathogens and rational vaccine
design, particularly in relation to HIV.

Ivan M. Roitt
Professor Roitt was born in 1927 and educated at King Edward’s School, Birmingham and Balliol College, Oxford. In 1956, together with Deborah Doniach and Peter Campbell, he made the classic discovery of thyroglobulin autoantibodies in Hashimoto’s thyroiditis which helped to open the whole concept of a relationship between autoimmunity and human disease. The work was extended to an intensive study of autoimmune phenomena in pernicious anaemia and primary biliary cirrhosis. In 1983 he was elected a Fellow of The Royal Society, and has been elected to Honorary Membership of the Royal College of Physicians and appointed Honorary Fellow of The Royal Society of Medicine. His current research is focused on cancer.

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Product details

Publisher

Wiley-Blackwell

Language

English

ISBN

9781405196833
1405196831

Released

12 edition
October 7, 2011

Page Count

560

About the Author

Dennis R. Burton

Ivan M. Roitt

Peter J. Delves

Seamus J. Martin

Description

Greetings, dear reader! In the exciting world of scientific progress, immunology plays a prominent role and we have aimed to bring this edition to the cutting edge of the latest discoveries. Highlights of the new updates include:
Tailoring of the adaptive immune response to pathogens, particularly in the skin by pattern recognition receptors
New insights into the interaction between antibodies and Fc receptors, and immunoglobulin genetics
Epigenetic control of T‐cell activation
T‐cell recognition of lipid antigens and beautiful high‐resolution images of interactions with other cells of the immune system
Expanded discussion of novel events in cytokine biology
Revised section on antibody interaction with viral proteins
Recent developments in vaccinology including RNA vaccines
Induction of cells suppressing a protective immune response by tumors, and recent breakthroughs in tumor immunotherapy
Induction and maintenance of immunosuppression to curb graft rejection
The role of inflammasomes in autoinflammatory disease … and much more! We try to maintain the chatty style characteristic of all earlier editions, imagining that you and the authors are on either side of a fireplace discussing the issues informally, which we hope makes the process of assimilation less painful and quite probably enjoyable.